OXRAMET 5/1000 14 Tablets

Oxramet 5 mg/1000 mg 

Oxramet 5 mg/1000 mg is a ‘antidiabetic medication’ used in conjunction with a healthy diet and exercise to treat type 2 diabetes mellitus. Additionally, 5 mg/1000 mg Oxramet reduces the risk of heart failure in patients with type 2 diabetes and cardiovascular disease. The metabolic disorder diabetes mellitus is characterized by abnormally high blood sugar levels. It occurs when insulin is ineffective at breaking down glucose to produce energy (insulin resistance) or when the pancreas (an organ beneath the stomach) produces insufficient or no insulin. In type 1 diabetes, the use of Oxramet 5 mg/1000 mg is contraindicated.

Metformin and Dapagliflozin are two diabetes medications found in Oxramet 5 mg/1000 mg. Metformin is a member of the drug class known as biguanides and is used to regulate blood sugar levels, especially in obese individuals. It acts independently of the pancreas to reduce blood glucose without increasing insulin secretion. Dapagliflozin belongs to the gliflozin class of medications. It functions by eliminating excess sugars through urine, thereby reducing blood sugar levels.

Take Oxramet 5 mg/1000 mg precisely as directed by your doctor. Oxramet 5 mg/1000 mg side effects include nausea, vomiting, diarrhea, headache, weakness, runny nose, vaginal infection, dizziness, changes in taste, and sore throat. Oxramet 5 mg/1000 mg may occasionally cause lactic acidosis (a rare but serious metabolic condition caused by an accumulation of lactic acid in the blood as a result of metformin use) or diabetic ketoacidosis (excessive synthesis of blood acids (ketones)). These negative effects are not universal and vary from person to person. Consult your physician if you experience uncontrollable side effects.

Oxramet 5 mg/1000 mg may cause hypoglycemia (low blood sugar); therefore, it is advised to consume a well-balanced diet with sufficient calories and to avoid vigorous exercise. Do not take or discontinue this medication without your doctor’s approval. Notify your doctor if you have a history of heart, kidney, or liver disease, breathing problems, blood disorders, dehydration, alcohol use, hypotension, or genital yeast infection before beginning Oxramet 5 mg/1000 mg. Alcohol consumption should be avoided while taking Oxramet 5 mg/1000 mg to reduce the risk of developing lactic acidosis. Oxramet 5 mg/1000 mg is contraindicated during the second and third trimesters of pregnancy, as well as during breastfeeding.

Indications for Oxramet 5 mg/1000 mg Type 2 Diabetes mellitus

Medicinal Advantages

A combination of Metformin and Dapagliflozin, Oxramet 5 mg/1000 mg is used to treat type 2 diabetes. Metformin is a biguanide that assists obese individuals in regulating their blood sugar levels. It acts independently of the pancreas to reduce blood glucose without increasing insulin secretion. In addition, it is known as an insulin sensitizer because it amplifies the effects of insulin. Metformin is distinctive among anti-diabetic drugs because it does not induce hypoglycemia (lowered blood sugar levels). Dapagliflozin belongs to the gliflozin class of medications. It functions by eliminating excess sugars through urine, thereby reducing blood sugar levels. In addition, 5 mg/1000 mg of Oxramet reduces the risk of heart failure in individuals with type 2 diabetes and cardiovascular disease. Oxramet 5 mg/1000 mg may be prescribed in addition to or as a substitute for other medications, as well as diet and exercise, to regulate blood sugar levels.

Tablet: Swallow the entire 5 mg/1000 mg Oxramet tablet with a full glass of water. Avoid chewing, crushing, and splitting the pill. To avoid hypoglycemia and gastrointestinal side effects, take Oxramet 5 mg/1000 mg with food if possible. Your doctor may start with a low dose and gradually increase it until the desired level of blood glucose control is achieved.

Storage Avoid direct sunlight and store in a cool, dry area.

Oxramet 5 mg/1000 mg Adverse Reactions

Nausea

Vomiting

Diarrhea

Pain in the head Weakness

Nose runny

Sexually transmitted disease

Dizziness

Changes in flavor

Throat inflammation

Acidosis lactica (rare)

Ketoacidosis in diabetics (rare)

Adverse Drug Reactions

Notify your doctor if you are currently taking any other anti-diabetic drugs so that the dosage of Dapagliflozin and Metformin can be adjusted appropriately. Do not discontinue Dapagliflozin and Metformin unless directed to do so by your doctor. The combination of Dapagliflozin and Metformin may cause hypoglycemia (low blood sugar); therefore, it is advised to consume a well-balanced diet with sufficient calories and avoid vigorous exercise. Inform your doctor if you have heart, kidney, or liver disease, breathing problems (asthma, obstructive lung disease), blood problems such as anemia (lack of red blood cells), vitamin B12 deficiency, pancreas problems/surgery, dehydration, alcohol use, low blood pressure, or genital yeast infection before taking Dapagliflozin and Metformin. Consuming alcohol while taking Dapagliflozin or Metformin may increase the risk of developing lactic acidosis. Neither Dapagliflozin nor Metformin should be taken during the second or third trimester of pregnancy or while breastfeeding. In such cases, your physician may recommend alternative diabetes medications. Dapagliflozin and Metformin are not recommended for patients younger than 18 years old.

Interactions Between Drugs

Metformin and Dapagliflozin may interact with diuretics (hydrochlorothiazide), analgesics (ibuprofen, celecoxib), acid-reducing drugs (cimetidine), asthma drugs, blood pressure-lowering drugs, and corticosteroids.

Alcohol consumption increases the likelihood of lactic acidosis.

Inform your doctor if you have heart, kidney, or liver disease, breathing problems, blood disorders, dehydration, alcohol use, or low blood pressure before taking Dapagliflozin with Metformin. Dapagliflozin and metformin are contraindicated in patients with moderate to severe renal impairment and metabolic acidosis/diabetic ketoacidosis.

Safety Recommendations

ALCOHOL

It is advised to abstain from alcohol consumption, as it may exacerbate adverse effects such as lactic acidosis and increase the likelihood of developing hypoglycemia.

PREGNANCY

Taking Dapagliflozin or Metformin during the second or third trimester of pregnancy is not advised. Additionally, your doctor may suggest additional medications to help you manage your blood sugar levels. If you are pregnant or planning to become pregnant, consult your physician prior to initiating Dapagliflozin and Metformin.

BREAST FEEDING

Due to the fact that they are excreted in breast milk, taking Dapagliflozin and Metformin while breastfeeding may be hazardous. Consult your physician for further information.

DRIVING

If your blood sugar is too high or too low, it could impair your ability to drive. If you have blurred vision, dizziness, or drowsiness as a result of severely low or high blood sugar, avoid driving or operating heavy machinery.

LIVER

If you have a history of liver disease or hepatic impairment and are prescribed Dapagliflozin and Metformin, inform your doctor.

KIDNEY

Dapagliflozin and metformin are contraindicated for patients with severe renal impairment/kidney disease. If you have a history of kidney disease and are taking Dapagliflozin and Metformin, inform your doctor.

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Advice on Diet and Lifestyle

If you are taking Dapagliflozin and Metformin more than once per day, follow your doctor’s instructions and take the medication at regular intervals. Do not take any additional over-the-counter medications, herbal supplements, or vitamin supplements while taking Dapagliflozin and Metformin without first consulting your pharmacist or doctor.

Maintain a high-fiber diet consisting of fruits, vegetables, and whole grains to help control your blood glucose.

Consume food at consistent intervals.

To keep your heart healthy, you should maintain a healthy weight and engage in regular exercise.

In addition, your doctor will teach you how to identify and manage the early symptoms of high/low blood sugar levels.

Simple changes in lifestyle can aid in the management of gastrointestinal side effects. These include consuming less sugar and fat, as well as avoiding carbonated beverages and foods that cause gas.

Special Guidance

It is recommended that you frequently monitor your blood sugar levels.

Your doctor may advise you to temporarily discontinue Dapagliflozin and Metformin if you are scheduled to undergo an x-ray or CT scan that requires the injection of a contrast agent.

While taking Dapagliflozin and Metformin, it is advised to monitor kidney function frequently.

Dapagliflozin and Metformin may cause a positive urine glucose test; therefore, inform your doctor in advance if you are taking these medications.

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Concern for Patients

Diabetes mellitus, also known as adult-onset diabetes, is a metabolic disorder characterized by high blood glucose levels. Type 2 diabetes occurs when insulin is ineffective at breaking down glucose to produce energy (insulin resistance) or when the pancreas (an organ beneath the stomach) produces inadequate or no insulin. This condition is more prevalent in people over the age of 40, but depending on the risk factors, it can also occur in children. Oral glucose-lowering medications and insulin injections are used to treat diabetes.

FAQs

Oxramet 5 mg/1000 mg contains the anti-diabetic medications Metformin and Dapagliflozin. These medications help to control blood sugar levels in patients with type 2 diabetes by removing excess sugars from the urine and enhancing the action of insulin.

Both Dapagliflozin and Metformin have the potential to cause low blood sugar (hypoglycemia), which can result in feelings of hunger, dizziness, anger, confusion, anxiety, or trembling. Therefore, it is advised to take Dapagliflozin and Metformin with food. To quickly treat hypoglycemia, it is advised to consume sugar sources with a rapid onset of action, such as fruit juices, hard candies, raisins, and regular cola.

Dapagliflozin and Metformin may be prescribed alone or in combination with other medications to regulate blood sugar levels. When taking Dapagliflozin and Metformin alone or in combination with other anti-diabetic medications, it is recommended to maintain a healthy diet and exercise regimen.

Patients with heart, kidney, or liver disease, breathing problems (asthma, obstructive lung disease), blood disorders (anemia, vitamin B12 deficiency), dehydration, alcohol use, low blood pressure, pancreas problems/surgery, and genital yeast infection should use Dapagliflozin and Metformin with caution. Dapagliflozin and metformin are contraindicated in patients with moderate to severe renal impairment and metabolic acidosis/diabetic ketoacidosis.

If you experience vomiting, stomach/abdominal pain, muscle cramps, a nauseous feeling, severe fatigue, difficulty breathing, or a decrease in body temperature and heart rate while taking Dapagliflozin with Metformin, it is imperative that you seek medical attention immediately, as these are symptoms of lactic acidosis. Metformin accumulation is associated with a rare but dangerous condition known as lactic acidosis. This is a medical emergency requiring immediate care. Consult your physician for further details.

Both Dapagliflozin and Metformin should not be taken with water pills or diuretics. Using Dapagliflozin, Metformin, and water pills concurrently dehydrates the patient and increases the risk of developing lactic acidosis.

Immediately administer the missed dose. If the next dose is approaching, however, you should skip the missed dose and resume your regular dosing schedule. Contrary to popular belief, the dose should not be doubled.