APREZO 20MG – Apremilast 4 tablets

About Aprezo 20 mg

Aprezo 20 mg belongs to the steroid (phosphodiesterase 4 (PDE4) inhibitors) medication family. It is used to treat Plaque psoriasis (scaly, itchy, red skin areas), psoriasis arthritis (inflammation of the joints in psoriasis patients), and oral ulcers. The illness psoriasis is persistent, painful, noncontagious, deactivating, and destructive. It can occur at any age but is most prevalent between the ages of 50 and 69. Psoriasis arthritis is a kind of arthritis that affects a small number of individuals with psoriasis.

Aprezo 20 mg includes Apremilast, an inhibitor of phosphodiesterase 4 (PDE4). Aprezo 20 mg reduces the signs and symptoms of psoriatic arthritis and psoriasis by preventing the activity of chemical messengers responsible for inflammation associated with these illnesses.

Take 20 mg of Aprezo as suggested by your doctor. Depending on your medical condition, you are instructed to take Aprezo 20 mg for as long as your doctor prescribes it. Possible side effects include diarrhea, vomiting, nausea, weight loss, and back discomfort. The majority of these Aprezo 20 mg side effects do not require medical care and subside with time. However, if the adverse effects continue, see your physician.

Depression that is worsening with suicidal ideation should not be treated with Aprezo 20 mg, since it may increase the risk of suicide. Before beginning Aprezo 20 mg, please contact your physician if you are allergic to Aprezo 20 mg or any of its components. Aprezo 20 mg is contraindicated in children and adolescents less than 17 years old. Before taking this 20 mg dose of Aprezo, consult your physician if you are pregnant or breastfeeding. Aprezo 20 mg has no effect on the ability to drive or operate machinery.

Plaque psoriasis, psoriasis arthritis, and mouth ulcers caused by Behcet’s illness are the indications for Aprezo 30 mg.

Medicinal Benefits

Aprezo 20 mg is used for the treatment of psoriatic arthritis; it reduces pain and inflammation and may assist improve joint flexibility. It is also used to treat moderate to severe plaque psoriasis (a skin disorder that causes red, scaly patches to grow in certain places of the body) in patients who might benefit from therapy. It is used to treat oral ulcers in patients with Behcet’s syndrome (a disease that results from blood vessel swelling in the body). Aprezo 20 mg acts by inhibiting the function of certain chemical messengers responsible for psoriatic arthritis and psoriasis-related inflammation, hence reducing the signs and symptoms of these illnesses.

Directions for Use

The 20 mg dose of Aprezo is available as a tablet. Take 20 mg of Aprezo orally. The dosage and duration of a medication are determined by the physician. Take 20 mg of Aprezo with or without meals. The Aprezo 20 mg tablet should be taken with a full glass of water. Avoid crushing, chewing, and breaking.

Storage

Place in a cool, dry location out of direct sunlight.

Side Effects of Aprezo 20 mg

Diarrhea

Vomiting

Nausea

Weight loss

Back pain

Drug Warnings

Before using Aprezo 20 mg, tell your doctor if you have ever experienced an allergic reaction (hypersensitivity). Please contact your doctor if you experience depression and suicidal thoughts before to taking Aprezo 20 mg. Inform your doctor if you have before using Aprezo 20 mg. If you have serious renal issues. Inform your doctor if you have unintentional weight loss while taking Aprezo 20 mg. Aprezo 20 mg should not be taken in the event of extreme nausea, vomiting, and diarrhea. Not suggested for usage in children and teenagers less than 17 years old. Before taking this 20 mg dose of Aprezo, consult your physician if you are pregnant or breastfeeding. Patients with extremely uncommon genetic galactose intolerance, complete lactase deficiency, or glucose-galactose malabsorption should not use Aprezo 20 mg.

Drug Interactions

Drug-Drug Interactions: Aprezo 20 mg may interact with tuberculosis-TB (rifampicin) and seizure/epilepsy medications (phenytoin, phenobarbital, carbamazepine).

No food-drug interactions have been identified.

Drug-Disease Interactions: Patients with depression, renal disease, or weight loss should not get apremilast.

Safety Advice

ALCOHOL

Limit your alcohol consumption, since it may aggravate psoriasis.

PREGNANCY

Before using Apremilast, it is essential to contact your doctor if you are pregnant or likely to get pregnant. While taking this Apremilast, you should avoid becoming pregnant.

BREAST FEEDING

It is unknown whether Apremilast passes into breast milk. Therefore, Apremilast should be avoided by nursing moms. Inform your physician right away before taking Apremilast.

DRIVING

Apremilast has no or a minor effect on the ability to operate motor vehicles and machinery.

LIVER

Apremilast should be used with caution, particularly if you have a history of liver disorders or problems. Your doctor may need to modify the dosage.

KIDNEY

Take Apremilast with caution, particularly if you have a history of Kidney illnesses or disorders. Your doctor may need to modify the dosage.

No Habit Forming

Diet & Lifestyle Advise

Physical activity aids in muscle strengthening and alleviates joint stiffness. Twenty to thirty minutes of walking or swimming might be beneficial.

Yoga may also aid in increasing joint flexibility and relieving pain.

Maintain a healthy weight with frequent low-stress activity and nutritious diet.

Resting the muscles via appropriate sleep can aid in lowering inflammation and swelling.

Follow heat or cold treatment, and routinely apply a cold or hot compress to the affected joints for 15 to 20 minutes.

De-stress by meditating, reading, having a warm bath with bubbles, or listening to relaxing music.

Additionally, acupuncture, massage, and physical therapy may be beneficial.

Consume antioxidant-rich foods such as berries, spinach, kidney beans, and dark chocolate.

Flavonoids-containing foods are anti-inflammatory. Included in this category are soy, berries, broccoli, grapes, and green tea.

Avoid smoking and drinking alcohol.

Special Advise

Apremilast is a medication that is well tolerated. Initial therapy may be accompanied by mild gastrointestinal distress.

Monitor your weight often since Apremilast may cause weight loss.

Notify your doctor promptly if you develop or suffer a worsening of depression, suicidal ideation, unexplained weight loss, or other mood changes.

Other Information :   This item is Not Returnable.

Disease/Condition Glossary

Plaque psoriasis is an inflammatory skin condition that causes red, scaly, thick, itchy, and painful spots on the skin, as well as the nails and scalp. It can occur at any age but is most prevalent between the ages of 50 and 69. Psoriasis can also be triggered by both internal and environmental factors, such as sunlight, moderate trauma, systemic medications, infections, and stress.

Psoriatic arthritis is an inflammatory condition of the joints that affects a small number of patients with psoriasis of the skin.

Behcet’s disease is a rare form of inflammatory disorder that affects several body organs. Oral ulcers are the most prevalent problem. It is a disorder that causes the body’s blood vessels to enlarge.

FAQs

Apremilast  may produce depression as a side effect. Additionally, the patient may induce suicidal ideation. In patients with a history of depression, apremilast should be avoided. If you acquire any of these symptoms, consult your physician immediately.

Apremilast is used to treat plaque psoriasis (skin lesions that are red, scaly, thick, itchy, and painful) and psoriatic arthritis (a condition that causes joint pain and swelling). It is a long-term therapy that may take up to 16 weeks to be effective.

Appetite suppression may be induced by apremilast, which may contribute to weight loss. You should routinely monitor your weight while on Apremilast therapy. In the event of a significant weight loss, see your physician. Your physician may consider discontinuing Apremilast.

While using Apremilast, you should not take rifampicin. Rifampicin interacts with the effectiveness of Apremilast by decreasing its concentrations. Consequently, you may not see any improvement after using Apremilast.